USS Independence (NCC-41452)

The USS Independence was an Ambassador-class Federation starship in service during the 24th century. By 2375, the Independence was under the command of Captain George Garfield.

In late 2375, the Independence was transporting Commander William T. Riker to attend the bicentennial celebrations for the signing of the Resolution of Non-Interference, when she was attacked by several Romulan Warbird's commanded by Sela near Sector 221-G. The Independence was quickly destroyed by the warbirds, but many crew managed to escape via escape pods. However, Sela ordered the escape pods destroyed and many were before the USS Excalibur intervened. (TNG novel: Double Helix #5: Double or Nothing).