Starfleet ship losses

This is a list of fictional starships in the Star Trek universe that have been lost or destroyed.

Ships
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Ambassador class
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 * USS Enterprise
 * NCC-1701-C
 * The Enterprise-C fought several Romulan warbirds before being destroyed in 2344.
 * USS Horatio
 * NCC-10532
 * The destruction of the Horatio in 2364 at Dytallix B was believed to have been caused by sabotage.
 * USS Yamaguchi
 * NCC-26510
 * Destroyed at the Battle of Wolf 359 in 2366.
 * USS Yamaguchi
 * NCC-26510
 * Destroyed at the Battle of Wolf 359 in 2366.

Antares class
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 * USS Antares
 * NCC-501
 * Destroyed by Charles Evans in 2266.
 * Destroyed by Charles Evans in 2266.

Apollo class
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 * USS Gage
 * NCC-11672
 * Destroyed at the Battle of Wolf 359 in 2366.
 * Destroyed at the Battle of Wolf 359 in 2366.

Challenger class
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 * USS Buran
 * NCC-57580
 * Destroyed at the Battle of Wolf 359 in 2366.
 * Destroyed at the Battle of Wolf 359 in 2366.

Cheyenne class
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 * USS Ahwahnee
 * NCC-71620
 * Destroyed at the Battle of Wolf 359 in 2366.
 * Destroyed at the Battle of Wolf 359 in 2366.

Constitution class
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 * USS Constellation
 * NCC-1017
 * Destroyed in 2267 by a planet killer.
 * USS Enterprise
 * NCC-1701
 * Destroyed in 2285 by Admiral James T. Kirk to prevent its capture by Klingon forces.
 * USS Intrepid
 * NCC-1631
 * Destroyed by a space-faring amoeba near the Gamma 7A System in 2268.
 * USS Excalibur (Star Trek)|USS Excalibur
 * NCC-1664
 * Destroyed by the USS Enterprise while under control of the M-5 multi-tronic computer in a war game in 2268.
 * USS Excalibur (Star Trek)|USS Excalibur
 * NCC-1664
 * Destroyed by the USS Enterprise while under control of the M-5 multi-tronic computer in a war game in 2268.
 * Destroyed by the USS Enterprise while under control of the M-5 multi-tronic computer in a war game in 2268.

Daedalus class
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 * USS Archon
 * NCC-189
 * Destroyed at Beta III in 2167.
 * USS Essex
 * NCC-173
 * Destroyed in 2167 by an electro-magnetic storm in the atmosphere of a Class M moon of planet Mab-Bu VI.
 * USS Horizon
 * NCC-176
 * Destroyed in 2168 at Sigma Iotia II.
 * USS Horizon
 * NCC-176
 * Destroyed in 2168 at Sigma Iotia II.

Danube class
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 * USS Gander
 * Unknown
 * Destroyed by the Jem'Hadar in 2375.
 * USS Ganges
 * NCC-72454
 * Destroyed by a T'lani vessel in 2370.
 * USS Mekong
 * NCC-72617
 * Destroyed in 2371 during the failed Cardassian and Romulan assault on the Founder's Homeworld in the Omarian Nebula.
 * USS Orinoco
 * NCC-72905
 * Destroyed in 2372 by the Cardassian separatist group "The True Way".
 * USS Yangtzee Kiang
 * NCC-72453
 * Crashed on a penal moon in the Gamma Quadrant in 2369, having been fired upon in orbit.
 * USS Yukon
 * NCC-74602
 * Destroyed by the USS Defiant in 2373 during an attempt by a Changeling infiltrator to use the runabout to blow up the Bajoran sun.
 * USS Gander
 * NCC-73918
 * Self-destructed to prevent it from falling into Dominion hands during a 2375 mission to capture a Breen energy dampening weapon.
 * USS Yukon
 * NCC-74602
 * Destroyed by the USS Defiant in 2373 during an attempt by a Changeling infiltrator to use the runabout to blow up the Bajoran sun.
 * USS Gander
 * NCC-73918
 * Self-destructed to prevent it from falling into Dominion hands during a 2375 mission to capture a Breen energy dampening weapon.
 * Self-destructed to prevent it from falling into Dominion hands during a 2375 mission to capture a Breen energy dampening weapon.

Defiant class
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 * USS Defiant
 * NX-74205
 * Destroyed by a Breen energy draining weapon in 2375 during the Second Battle of Chin'Toka of the Dominion War.
 * USS Valiant
 * NCC-74210
 * Destroyed by the Dominion in 2374.
 * NCC-74210
 * Destroyed by the Dominion in 2374.

Excelsior class
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 * USS Cairo
 * NCC-42136
 * Lost, presumed destroyed by the Jem'Hadar, in 2374 near the Romulan Neutral Zone.
 * USS Grissom
 * NCC-42857
 * Destroyed by the Dominion in 2375 with the loss of all but six hands.
 * USS Melbourne
 * NCC-62043
 * Destroyed by the Borg at the Battle of Wolf 359 in 2367.
 * USS Roosevelt
 * NCC-2573
 * Destroyed by the Borg at the Battle of Wolf 359 in 2367.
 * USS Roosevelt
 * NCC-2573
 * Destroyed by the Borg at the Battle of Wolf 359 in 2367.
 * Destroyed by the Borg at the Battle of Wolf 359 in 2367.

Galaxy class
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 * USS Enterprise
 * NCC-1701-D
 * Stardrive section destroyed by a warp core breach following confrontation with Klingon Bird Of Prey commanded by the Duras sisters in 2371. Saucer section crash-landed on surface of Veridian III shortly thereafter.
 * USS Odyssey
 * NCC-71832
 * Destroyed by a Jem'Hadar attack ship in the Gamma Quadrant in 2370.
 * USS Yamato
 * NCC-71807
 * Destroyed by computer failure caused by an Iconian computer virus in 2365.
 * USS Yamato
 * NCC-71807
 * Destroyed by computer failure caused by an Iconian computer virus in 2365.

Hope class

 * USS Pasteur
 * NCC-58925
 * Destroyed by a warp core breach in an alternate future in 2395 following an attack by two Klingon Negh'Var class starships.
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