Lysergic acid diethylamide

Lysergic acid diethylamide, or LSD, was a powerful hallucinogen used on Earth. It is synthesized from lysergic acid derived from ergot, a grain fungus that typically grows on rye and was first synthesized by Swiss chemist Albert Hofmann. The extra-medicinal use of the drug in Western society during the mid-20th century led to a political firestorm that resulted in the banning of the substance. During the Cold War intelligence agencies were interested in using LSD for interrogation and mind control, as well as for large-scale social engineering. The CIA research on LSD, most of which was done under Project MKULTRA began in the 1950s and continued until the late 1960s. The CIA, MI6, and the United States Army experiments became highly controversial when they became public knowledge in the 1970s. These projects seem to have concluded that LSD was of little practical use as a mind control drug and moved on to other drugs.

A similar drug, anodyne, was widely used on Mythra to controll the populous. 

In 1986, James T. Kirk confused LSD with LDS.