Isaac Newton

Sir Isaac Newton was a male Human scientist in the 17th century, credited with inventing calculus and what would later be termed Newtonian physics.

Newton once encountered a Q known as Quinn, who was responsible for jostling an apple tree and causing an apple to drop on Newton's head. (VOY episode: "Death Wish")

Lieutenant Commander Data once created a holodeck version of Newton, along with Albert Einstein and Stephen Hawking, in order to observe their interactions in a game of poker. (TNG episode: "Descent, Part I")