Cordrazine

Cordrazine was a strong chemical stimulant and was used by Starfleet doctors in the 23rd century during emergency medical situations, and was primarily used to stimulate the heart during cardiac arrest.

Excessive amounts of cordrazine has been known to cause temporary dementia and violent paranoia. In 2267, Dr. Leonard H. McCoy accidentally injected himself with a large dose of cordrazine. He immediately suspected that his crewmates were trying to kill him, and escaped to the planet Gateway. (TOS episode: "The City on the Edge of Forever", and novel: The Klingon Gambit).

By the 24th century, a more potent form of cordrazine had been developed, and was named tricordrazine. (TNG episode: "Ethics").