O'Brien

O'Brien maybe refer to:


 * Miles O'Brien - The TNG and DS9 character.
 * Miles O'Brien - The mirror universe counterpart of Miles.


 * O'Brien family:
 * Keiko O'Brien - The wife of Miles.
 * Kirayoshi O'Brien - The second daughter of Miles and Keiko.
 * Michael O'Brien - The father of Miles.
 * Molly O'Brien - The first daughter of Miles and Keiko.
 * Sean Aloysius O'Brien - An ancestor of the O'Brien family.