United Earth Space Probe Agency

The United Earth Space Probe Agency (abbreviated UESPA) was an organization controlled by the United Earth responsible for space exploration.

History
The agency launched the Friendship One probe in 2067 toward the Delta Quadrant as part of a series of unmanned exploration. 

Bu the 2130s the United Earth Starfleet had taken UESPA's place as Earth's leading exploratory agency, but the two would continue to cooperate. 

UESPA personnel would also aid in the construction of the Enterprise (NX-01) in 2150. (Star Trek: Enterprise)

UESPA would continue to help control Starfleet vessels into the 2260s. James T. Kirk would report the destruction of the USS Antares (23rd century) to UESPA. Kirk would also inform John Christopher that UESPA was the USS Enterprise (NCC-1701)'s operating authority. 

Alternate Realities
In one alternate timeline the was a UESPA vessel prior to capture by Klingons.