The Agni Cluster was a group of G class stars located in Federation space near Ferengi territory.

In 2383, the USS Enterprise-E conducted a survey of the Agni Cluster to locate class M planets suitable to create new colonies for the remaining refugees of the Borg Invasion of 2381. While there, they discovered the Intrepid, which had gone missing over two hundred years earlier. (TNG novel: Indistinguishable from Magic)

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