Alfred or Alfredo could refer to:
- People
- Alfred Bleikoff, a 20th century Nobel Prize-winning physicist
- Alfred Bowles, CO of the USS Huxley
- Alfredo Goveia, an ambassador with the Starfleet Diplomatic Corps
- Alfredo Della Guardia, an engineer aboard the USS Enterprise-D
- Alfred Hitchcock, a noted 20th century film director
- A.E. Housman, a.k.a. Alfred Edward Housman, an English poet
- Alfred Hume
- Alfredo Pedillo Jose, a 20th century Earth resident
- Alfredo Juarez, a lieutenant aboard the USS Enterprise-D
- Alfred Korzybski, a 20th century Human philosopher
- Alfred Nobel, inventor of dynamite, creator of the Nobel Prize
- Alfred Parks, a doctor on Aquila II
- Alfred Tennyson, a 19th century Human poet
- Alfred Wallace, a 19th century English anthropologist
- Alfred North Whitehead, a 20th century Human philosopher
- Mary Alfreds, a casualty of Earth's Vietnam War
- Starships
- USS Alfred North Whitehead, a 23rd century Federation starship
- Other topics
- Gamma Trianguli Boa Alfredo
- Real-world topics
- Alfredo Alcala, a comic strip artist
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