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Arthritis was a medical condition affecting the sufferer's joints, caused by joint inflammation and commonly affecting the elderly. Mild arthritis caused stiffness and aches, while severe arthritis rendered hands and other limbs twisted and unusable. (FASA RPG - The Orions module: Book of Deep Knowledge)

It was one of a number of handicaps that randomly afflicted Grey Orions of any age, due to their genetic mutilation. (FASA RPG - The Orions module: Book of Deep Knowledge)

Hupyrians possessed a genetic disorder similar to arthritis. (DS9 novel: Avatar, Book One)

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