Beta Portolan was a star system, located somewhere in the space of the galaxy's Alpha or Beta Quadrants, in or near the 23rd century boundaries of Federation space. Beta Portolan was attacked by blastoneuron neural parasites. (TOS episode: "Operation -- Annihilate!")

The stellar notation using the Greek language letter "beta" indicates that there might be a star group or constellation of some sort named "Portolan", of which Beta Portolan would logically be indicated to be the second most prominent star or system.

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