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Memory Beta, non-canon Star Trek Wiki
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The cerebral cortex is part of the brain.

This neurological location was where Ceti eels would wrap themselves around, in a humanoid host. This left said-host vulnerable to suggestion. As the eels grew, putting pressure on the cortex, the victim would experience maddening pain to the point of death. (TOS movie: The Wrath of Khan)

The Tigan interface technology downloaded information directly into the cerebral cortex. (TNG comic: "History Lesson")

In 2273, Commander Spock's cerebral cortex was traumatized after a staggeringly powerful mind-meld with V'Ger; through the stored data pattern of what was once Lieutenant Ilia. (TOS movie: The Motion Picture)

The victims of the Unclean had their cerebral cortexes amalgamate with other victims. (DS9 - Invasion! novel: Time's Enemy)

Almost 100 years later, in 2372, Lon Suder's violent, emotional synaptic patterns were downloaded (like raw data) into Tuvok's mesiofrontal, cerebral cortex. (VOY episode: "Meld")

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