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Charles Robert Darwin (12 February 1809 – 19 April 1882) was a 19th century Human scientist who proposed that natural selection allowed adaptable species to survive in changing environments. His 1859 book On the Origin of Species established evolution as a theory.

In 2269 (stardate 6451.3), Leonard McCoy suggested that Doctor Katalya Tremain was on the same level with Darwin. (TOS novel: Vulcan!)

In 2277, during a brief excursion to Marris V to collect plant and animal specimens, Hikaru Sulu was reminded of Darwin's studies of the Galápagos Islands. Sulu equated the impact of those studies to science with anthropologist Alfred Wallace's exploration of South America and biologist Charles Jackson's time on Rigel III. (TOS - Star Trek II Short Stories short story: "Wild Card")

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