Chen could refer to:
- People
- Chen (Admiral), commanding officer of Starbase 15 in 2273.
- Chen (USS Discovery)
- Chen (alternate reality USS Enterprise), alternate reality USS Enterprise crewmember
- Chen (Ensign), an ensign aboard the USS Enterprise in 2281
- Chen (Donatu V), a person who lost their life on Donatu V
- Chen (Lieutenant), USS Stargazer crewmember
- Chen (USS Lincoln), USS Lincoln security crewmember
- Chen (USS Marconi), USS Marconi crewmember
- Chen (Yeoman), a crewmember of the Shepherd in 2259
- Grace Chen, a Starfleet Academy cadet in the Kelvin timeline
- Jonathan Chen, a lieutenant aboard the USS Enterprise in 2268
- Robert Chen, Governor of California
- Samuel Chen, chairman of the physical education department at Starfleet Academy
- T'Ryssa Chen, a Vulcan/Human hybrid aboard the USS Enterprise-E
- Real-world topics
- Mike Chen
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