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Memory Beta, non-canon Star Trek Wiki
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Cystic Fibrosis was a medical condition affecting the sufferer's lungs and others, causing them to fill with fluid and suffocate.

A sufferer of cystic fibrosis needed to have these fluids drained on a regular basis. They were also more susceptible to respiratory and lung infections.

It was one of a number of handicaps that randomly afflicted Grey Orions, due to their genetic mutilation. (FASA RPG - The Orions module: Book of Deep Knowledge)

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