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Gabrielle Carlotti was a Starfleet officer who served as Doctor Phillip Boyce's head nurse on the USS Enterprise.

Carlotti was born on New Milan, a planet destroyed by the Chakuun, subject race of the Tholians, during a Tholian expansionist program. Of her family, only her and her two brothers survived. They moved to New Venice, a colony on Mars, and later to Florence, Italy with their Aunt Olivia.

Carlotti's service record described her as bright and outgoing, if a little intense. Before coming aboard the Enterprise, she served on the USS Redoubt and the USS Nelson. Carlotti was haunted by what she had suffered at the hands of the Chakuun, frequently having bad dreams about searching for her parents and finding a Chakuun, but Doctor Boyce was helping her pull through it all.

In 2255, Carlotti encountered a shipwrecked Chakuun cohort general on the surface of Theta Kalyb. The two learned much about each other's cultures, and when the cohort general was rescued she ordered a Chakuun retreat from Theta Kalyb. This went a long way toward stemming Carlotti's hatred of the Chakuun, and she was finally able to find peace. Carlotti's most important breakthrough was the discovery that the Tholians consider territorial boundaries fluid and shifting, accounting for some of their apparently irrational claims.

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