Gagarin could refer to:
- Starships and vehicles:
- Gagarin-class (23rd century), a variant of the Oberth-class
- Gagarin-class (24th century), a cruiser class
- Gagarin-class (25th century), a battlecruiser class based on the Shepard-class design.
- Gagarin-class (warpshuttle)
- USS Gagarin (NCC-1309, Shepard-class)
- USS Gagarin (scout)
- USS Gagarin (Oberth-class)
- USS Gagarin (NCC-25306)
- USS Gagarin (Saber-class)
- VK Yuri Gagarin
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