The Garodon V Penal Colony was a high security penal colony located on the Federation world Garodon V. The colony had been established prior to the mid 23rd century. The penal colony's security was handled by Starfleet.

The colony shared Garodon V with a small civilian colony. The penal colony was isolated from the civilian colony and was located over 1,000 kilometers from any other population centers on the planet.

One of the colony's inmates was Hisayo Fujimura. Fujimara had been sent to the colony for crimes she committed during the Tarsus IV Massacre, and those committed while attempting to help former Governor Kodos escape justice. In the 2250s, Shannon Moulton travelled to Garodon V to interview Fujimara for her book The Four Thousand: Crisis on Tarsus IV. (DSC novel: Drastic Measures)

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