Hamilton could refer to:
- People
- Hamilton (USS Voyager), an officer aboard the USS Voyager
- Hamilton Sam, a technician on Sheridan's World
- Alexander Hamilton, a founding father of the United States of America
- Alexander C. Hamilton, a 22nd century Starfleet admiral
- Ham Hamilton, an officer aboard the USS Bozeman
- Jane Hamilton, CMO of the USS Defiant
- Varn Hamilton, a starbase psychiatrist on Tau Delta IX
- Places
- Hamilton, a city on Earth
- Starships
- USS Hamilton (NCC-1145), a Constitution-class starship
- USS Hamilton, a 24th century Federation starship
- Real-world topics
- Hamilton Collection, a producer of licensed Star Trek merchandise
- Laurell K. Hamilton, a TNG novelist
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