Heisenberg could refer to:
- People
- Heisenberg (officer), transporter chief of the USS Trident
- Jochen Heisenberg, chairman of the physics department at Starfleet Academy
- Scott Heisenberg, a transporter chief stationed at Old City Station on Earth
- Werner Heisenberg, a noted 20th century theoretical physicist
- Starships and vehicles:
- Heisenberg (ship)
- USS Heisenberg (Daedalus-class)
- USS Heisenberg (23rd century)
- USS Heisenberg (Nebula-class)
- USS Heisenberg (Leviathan-class)
- USS Heisenberg (NCC-1251)
- Technology
- Heisenberg compensator, a component of transporter technology
- Other topics
- Heisenberg's Uncertainty Principle, an aspect of quantum mechanics
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