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Horace Tiberius Mudd was a grandson of Harry Mudd. His middle name originated from his grandfather's fondness for James T. Kirk.
In the year 2371, Mudd came to Deep Space 9, where he sold bio-engineered animals from the Gamma Quadrant to Quark. The animals later ran amok on the station. (DS9 comics: "Mudd's Pets, Part I", "Mudd's Pets, Part II")