Hypothermia is a medical condition where the core body temperature of a body drops below the required temperature needed for normal body functions.

In 2268, Cervantes Quinn used a medical tricorder on himself and discovered that he was suffering from hypothermia and hypoxia. He cured the hypothermia with some tri-ox compound. (VAN - Declassified novella: The Stars Look Down)

In 2273, when the Federation SW7-class shuttlecraft Halley was damaged within the Hohweyn system, Doctor Leonard McCoy tried to prevent Pavel Chekov from getting hypothermia. (TOS novel: The Kobayashi Maru)

In 2368, Jean-Luc Picard and Geordi La Forge prevented the Legarans from succumbing to hypothermia after a Romulan agent had sabotaged their environmental systems. (TNG short story: "Last Words")

In 2376, when the shuttlecraft Venture was disabled on the far side of the Bajoran wormhole, Jake Sisko wondered when hypothermia would set in. (DS9 novel: Rising Son)

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