The Institute for Starfleet Strategic Initiatives was an institution that existed within the Federation Starfleet.
History and specifics[]
In 2374, it was held by the Institute that the ability to create stable wormholes between any two points in space would be a development that will make te Cochrane Warp drive obselete. This prompted Starfleet in the study of Badlands-type phenomena in order to determine if they were capable of aiding in the creation of a stable wormhole. (TOS novel: Spectre)