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The Ionite Nebula was a nebula. Luria was located near the nebula.
Dahar Master Kor once fought a Romulan force in the Ionite Nebula. (ST reference: The Klingon Art of War)
In 2256, Lurian pirates operated in the Ionite Nebula. (DSC novel: The Enterprise War)
In 2372, Drex questioned why Morn was living so far away from the Ionite Nebula. (DS9 episode: "The Way of the Warrior")