Irene Hansen was a female Human living on Earth. She was the sister of Magnus Hansen and the aunt of Annika Hansen (aka Seven of Nine).
After the USS Voyager returned to the Alpha Quadrant, Seven of Nine went to live with Irene Hansen. (VOY novel: Homecoming)
By 2381, Irene had an incurable progressive neurological disease and was slowly dying; Seven noted that she was the only thing to bring her comfort, and watching her condition degrade was like observing a slow motion assimilation. (ST - Destiny novel: Mere Mortals)
Irene Hansen was suffering from Irumodic Syndrome. The Doctor, amongst other projects, was trying to find a cure for her. Irene later died of her illness. (VOY novel: Unworthy)