- "I read every transcript of every mission. I thought I was prepared, that I knew what to expect. Boy, was I wrong."
- —Jeffrey Pierce, 2154[src]
In 2154, Pierce signed on to Enterprise (NX-01) following its refit after returning from its mission in the Delphic Expanse. On May 17 of that year, Pierce was one of nine crew members, including Commander T'Pol, who were abducted by the Orion Syndicate. After being brought to the slave market on Verex III, Pierce was purchased by Captain Jonathan Archer who used his deactivated restraint to free and rescue the rest of the ship's abducted crew members. (ENT episode: "Borderland")