In the year 2371, the Federation starship the USS Equinox had inadvertently violated the space of the Krowtonan Guard in its first week after being stranded in the Delta Quadrant. When the Equinox proceeded through Krowtonan territory, the Guard attacked the ship, which lost 39 crewmembers, more than half of the ship's complement.
The Krowtonan Guard covered a portion of region beyond the coreward Nekrit Expanse, ca. 70.000 ly from Sol. The Guard lay between the rimward Haakonian Order and the coreward Vidiian Sodality. (ST reference: Star Charts)