- ISS Equinox
- ISS Esquiline
- ISS Europa
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- ISS Excalibur (NCC-94547)
- ISS Excelsior (NC-2015-I)
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- ISS Excelsior (NCC-2000-D)
- ISS Exeter
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- ISS Fortuna (NC-59650-A)
- ISS Fortuna (NC-97300)
- ISS Gagarin (NCC-1309)
- ISS Gagarin (NCC-97930)
- ISS Galaxy (NCC-0000)
- ISS Galaxy (NCC-70637)
- ISS Gryphon
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- ISS Intrepid (NCC-74600-A)
- ISS Intrepid (NCC-74621-B)
- ISS Invincible
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- ISS Lexington (NCC-1709)
- ISS Lexington (NCC-98355)
- ISS Liebig (NC-30478)
- ISS London
- ISS Luna (NC-32101-E)
- ISS Luna (NCC-80101)
- ISS Luna (NCC-80104)
- ISS Magee
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- ISS Merlin
- ISS Miranda (NCC-1805-B)
- ISS Miranda (NCC-1805-C)
- ISS Mobius
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- ISS Monitor
- ISS Monterey (NCC-1805-B)
- ISS Monterey (NCC-1805-C)
- ISS Monterey (NCC-42043)
- ISS Monterey (NCC-91846)
- ISS Navras
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- ISS Nova (NC-64515-F)
- ISS Nova (NCC-73515-B)
- ISS Nova (NCC-73515-C)
- ISS O'Brien
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- ISS Potemkin
- ISS Prometheus (NCC-59650)
- ISS Prometheus (NCC-59650-A)
- ISS Punisher
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- ISS Shenzhou
- ISS Shenzhou personnel roster
- ISS ShiKahr (NC-1021-R)
- ISS ShiKahr (NCC-91846)
- ISS Shran (NCC-1413)
- ISS Shran (NCC-91413)
- ISS Sirius
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- ISS Sovereign (NC-33977-C)
- ISS Spock
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- ISS Vanguard
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- ISS Venture (NCC-170147)
- ISS Venture (NCC-71954)
- ISS Vesta
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- ISS Voyager (ISS-74656-A)
- ISS Wells
- ISS Yamato
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- ISS Yorktown (Constitution class)
- ISS Yorktown (NCC-98300)
- ISS da Vinci
- IUES Ashoka
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- IUES Enterprise I
- IUES Kanlee
- IUES Kumari I
- IUES Kumari II
- IUES Ravis
- IXS Enterprise
- I Am Become Death
- I Am Captain Kirk
- I Am Klingon
- I Am Mr. Spock
- I Have Broken the Prime Directive
- I Have Heard the Mermaids Singing
- I Have No Bones Yet I Must Flee
- I Sing of Arms
- I Sing of Arms and Heroes
- I Wanna Hold Your Moneybelt
- I Will Survive
- Iach'tu Prime
- Iach'tui
- Iacovino
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- Iad
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- Iadara Colony
- Ian
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- Ian (disambiguation)
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- Ian Andrew Troi II
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- Ian Karapips
- Ian Kyle Riker
- Ian Legatt
- Ian Mackenzie
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- Ianara
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- Iban
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- Ibiza
- Iblis
- Iblis (disambiguation)
- Ibmar Zannakir
- Ibo
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- Ibrahim (Ensign)
- Ibranhai Taraja
- Ibsen
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- Icaria Prime
- Icarus
- Icarus (NCC-1701/3)
- Icarus (myth)
- Icarus (science vessel)
- Icarus (space shuttle)
- Icarus II
- Icarus IV
- Icarus class
- Icarus plague
- Iccobar
- Ice-goat
- Ice Journey
- Ice Planet
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- Ice age
- Ice cream
- Ice cutter
- Ice fern
- Iceclaw
- Iced neth
- Iced tea
- Iceland
- Iceland (disambiguation)
- Icheb
- Ichi
- Ichthyan
- Icoberry
- Icoberry jam
- Icoberry juice
- Icoberry sauce
- Icoberry torte
- Icolah
- Icon painting
- Iconia
- Iconia (star)
- Iconian
- Iconian Empire
- Iconian Resistance
- Iconian War
- Iconian War (STO)
- Iconian gateway
- Iconian portal
- Iconian software weapon
- Iconoclast-series
- Icor
- Icor IX
- Icorian
- Idaho
- Idaho (disambiguation)
- Idaja
- Idanian
- Idanian Clans
- Idelson
- Iden
- Identi-loc reading
- Identification beam
- Identification bracelet
- Identity Crisis
- Identity Crisis (eBook)
- Identity Crisis (episode)
- Identity disc
- Idiom
- Idises
- Idit Kahayn
- Idix
- Idol
- Idol Threats
- Idran
- Idran Cluster
- Idran I
- Idran II
- Idran IV
- Idran Prime Shipyard
- Idran sector
- Idrani
- Idris
- Idris flower dust
- Idryll
- Idryllglicium
- Idun Asmund
- Iefnohuu
- Ies Bredell
- If
- If I Lose Thee...
- If Memory Serves
- If Wishes Were Horses
- Iffalian
- Ifnik
- Ifrea-3
- Ifukube
- Ifukube Veil
- Igaaren
- Igel
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- Igo sector
- Igor Knezevic
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- Ih'tanu
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- Iiefni'liss
- Iiefnidro
- Iiehdro
- Iiliy
- Ijarna
- Ijik
- Ikaal
- Ikalia
- Ikassa bark
- Ikasun system
- Ikat'ika
- Ike Clanton