The Hopi-Pueblo nation was a tribe of humans that lived on the planet Mars by the 22nd century. They consisted of Native American tribes that followed similar actions as their eastern cousins that formed the Iroquois Confederation. The Hopi-Pueblo were members of the southwestern tribes that found a relocation to Mars more preferable to surrendering their sovereignity to the United Earth government.

In 2155, a chief representative of the Hopi-Pueblo nation was Qaletaqu with his father Katowa being the chief of the tribal government. They were involved in talks over the recent skirmishes with the Romulan Star Empire and felt displeased at the lack of the Vulcan government's aid to its Coalition members. (ENT novel: Beneath the Raptor's Wing)

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