In 2364, she transferred to the Galaxy-class USS Enterprise-D, under the command of Captain Jean-Luc Picard. Kadohata was assigned to the sensor room, where she worked under the direct supervision of the ship's operations manager and second officer, Lieutenant Commander Data.
After the destruction of the Enterprise in 2371, Kadohata was assigned aboard its replacement, the Sovereign-class USS Enterprise-E, again under the direct supervision of Lieutenant Commander Data and the ultimate command of Captain Picard. She served as relief operations manager when Data temporarily commanded the Enterprise during a mission to rescue Picard and Captain Benjamin Sisko on the planet B'Leva.
When Data was offered promotion to first officer of the Enterprise in 2379, he selected Kadohata as his successor as operations manager and second officer. She accepted, but took maternity leave before assuming her new duties. She returned to the Enterprise in early 2380.
During the Borg incursion later that year, Lieutenant Commander Kadohata led a mutiny aboard the Enterprise against Captain Picard and several other members of the Enterprise's senior staff, in response to their willful disobedience of orders from Fleet Admiral Alynna Nechayev. Though she briefly assumed command, Kadohata quickly deferred to Picard's judgment when the Enterprise came under Borg attack.
Following the battle, she declined to transfer from the ship, accepting Captain Picard's offer to remain aboard. Shortly thereafter, she was promoted to full commander, presumably on Picard's recommendation.
Borg Invasion of 2381
In 2381, Kadohta was on duty and announced the damage to Ramatis III to the Enterprise Bridge during the Borg Collective's invasion. Realizing that Starfleet was having difficulty containing the invasion of the Borg, she called a midnight planning and brainstorming session which included Rennan Konya, Beverly Crusher, and Geordi La Forge. Although the Borg had adapted to the technological and biological weapons that La Forge and Crusher had previously developed, the quartet worked on applying the technology from the transphasic torpedoes to their shields and other weapons, but the phasers weren't designed to handle the load.
After joining forces with the USS Aventine, Kadohata supervised the efforts to integrate their sensor inputs. The sensors revealed not a single subspace tunnel, but twenty-seven. When it became clear that protecting the tunnels would not be possible, Kadohata sent a warning message to her husband and children to leave Federation space, using veiled references to Judi and Adams and their move to Kennovere.
As the Enterprise scouted the tunnels, they encountered Hirogen fighters. The ship was boarded, and Kadohata participated in the defense of the bridge. When the Enterprise finally returned to the Azure Nebula, Kadohata picked up the distress call from USS Voyager.
At the end of her leave, Kadohata joined Beverly Crusher aboard the USS Genesee for a special mission on behalf of the Federation Displaced Persons Agency to investigate conditions at the iy'Dewra'ni refugee camp on Pacifica. Kadohata was instrumental in ensuring the camp received additional industrial replicators, and that the safety of younger camp residents was addressed. When the Enterprise arrived at Pacifica to assist their efforts, Kadohata requested to be allowed to remain, on detached duty to the DPA. This new assignment had the benefit of allowing her to remain in one location, and in relative proximity to her family on Cestus III. 
While aboard the Firenze, Kadohata was romantically involved with the ship's flight controller, Lieutenant Ricardo Torres. Torres transferred to the Enterprise with Kadohata in 2364, but their relationship ended shortly after the ship's maiden mission to Deneb IV, during which Torres was badly shaken by encounter with the semi-omnipotent being known as Q. A number of other shipboard relationships followed for Kadohata, but all were short and ended badly.
She met her eventual husband, Vicenzo Farrenga, at a baseball game on Cestus III between the Port Shangri-La Seagulls, for whom Kadohata's sister played shortstop, and the Palombo Sehlats, whose general manager was Farrenga's father. They had a daughter, Aoki Farrenga, in 2374, and a pair of twins, Colin and Sylvana, in 2379. She was probably home at Cestus III, when the Gorn Crisis occured.
While aboard the Enterprise, Kadohata communicated with her family in real time whenever she could. One night during the invasion of the Borg Collective in 2381, gamma shift operations manager Sean Milner contacted Kadohata just before 0500 hours so that she could utilize a communications window to speak to her family. Milner had convinced first officer Worf to call in a few favors to allow them to route the communication through Klingon subspace boosters. During the Borg Invasion of 2381, Miranda contacted her husband and covertly tried to tell him to leave Cestus III, using Judi and Adams as a veiled signal, as Starfleet officers were prohibited from discussing intelligence over an open subspace communications channel. 
Alternate timelines and realities
In an alternate timeline in which the Cardassian Union never withdraw from Bajor and discovered the Bajoran wormhole, Lieutenant Kadahota replaced Data as Operations Manager of the USS Enterprise-E when Data was assigned as permanent captain of the USS Sutherland. She was killed in action during a mission undertaken by the Enterprise to destroy the Bajoran wormhole to prevent the passage of Dominion vessels into the Alpha Quadrant to aid the Cardassians. (TNG - Myriad Universes novel: A Gutted World)
Starfleet service record
|location||assignment||dates||rank or rate||assignment insignia||rank insignia|
|USS Firenze||junior officer||circa 2363, until 2364||lieutenant junior grade|
|USS Enterprise-D||Sensor room officer||from 2364||lieutenant junior grade|
|relief operations manager||until 2371||lieutenant|
|USS Enterprise-E||relief operations manager||2372-2379||lieutenant|
|second officer/operations manager||2379-2380||lieutenant commander|
|USS Enterprise second officer
|USS Enterprise operations manager
unknown, eventually Ravel Dygan
|USS Enterprise (NCC-1701-E) senior staff|
|commanding officers:||M. Bateson • J.L. Picard • W.T. Riker • Data||first officers:||W.T. Riker • Data • Worf||second officers:||G. Bush • Data • M. Kadohata • G. La Forge|
|watch officers||Evan • Heyes • Lynley • Havers||chief medical officers:||B. Crusher • Stevenson||ship's counselors:||D. Troi • T'Lana • Hegol D.|
|chief engineers:||M. Scott • G. La Forge||operations managers:||Data • M. Kadohata • R. Dygan||flight controllers:||S. Hawk • S. Nave • J. Faur|
|security chiefs:||L. Addison • P. Daniels • Rowan • B. Leyoro • R. McAdams • C. Vale • S. Nave • L. Battaglia • Z. Leybenzon • J. Choudhury • A. Šmrhová|
|see also: engineering personnel • medical & counseling personnel • operations personnel • pilots & flight control personnel • security & tactical personnel • sciences personnel • miscellaneous • unnamed|
|USS Enterprise NCC-1701-E operations personnel|
|chief of operations||Data • M. Kadohata • R. Dygan|
|other operations personnel||A. Berardi • S. Milner • J. Rosado|
|see also: Senior staff • Engineering • Flight Control • Medical and Counseling • Operations • Science • Security • Misc. • Unnamed|