Missiles were a type of projectile weapon used by a variety of species and organisations.

Einstein class vessels were equipped with Several Photonic missile launcher Turrets that launch Several Energized Warheads in Rapid Fire. (TOS movie & novelization: Star Trek)

In the alternate reality created by the temporal displacement of the Narada, fighter-type vessels, such as the Federation Interceptor-class and Romulan Gladius-class, were armed with missiles. Pirates, operating space pirate vessels, were also heavily armed with missiles, able to fire multiple seeking missiles. (TOS video game: D-A-C)

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