NX-74205

NX-74205 could refer to:

• USS Defiant (NX-74205) (I), Defiant-class prototype
• USS Defiant (NX-74205) (II), Defiant-class starship, formerly the USS São Paulo
• USS Defiant (NX-74205) (III), a Vigilant-class ship
• ISS Defiant (NX-74205), Defiant-class starship

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