Neumenedes was a star system, located somewhere in the galaxy's Alpha or Beta Quadrants, in or near the 23rd century boundaries of Federation space.
History and specifics[]
Neumenedes was not far from Iskonia or Starbase 18.
In the year 2274, the Federation starship USS Enterprise headed to the Neumenedes system for shore leave, but were diverted for a priority mission before they could arrive. (TOS comic: "The Wristwatch Plantation")