Othello could refer to
- Shakespeare
- Othello (play), a play by William Shakespeare
- Othello (character), the titular character in Shakespeare's play
- Locations
- Othello (planet), a Federation planet in the Jarvis Alpha system
- Othello 1, a space station laboratory
- People
- Othello Beck, a famed physician and researcher
- Othello Beck's wife, a Vulcan stricken with Logan's disease
- Starships
- USS Othello, a Venture-class starship
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