The Quist were a spacefaring civilization native to a homeworld located somewhere in the galaxy's Alpha or Beta Quadrants.

The United Federation of Planets made first contact with the Quist in the 2360s, when an individual of the species boarded Starbase 189. This individual sped into a reception for a visiting admiral (an event Jefferson Blackmer attended), terrifying everyone and nearly igniting a war with the previously unknown species. (ST - The Fall novel: Revelation and Dust)

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