In the mirror universe, the Sacred Chalice was a brothel located on Betazed and operated by Lwaxana Troi. It served as the last refuge of the Betazoid race after the Terran Empire attacked the planet.

In 2371, Gul Taqut and Andrul Taqut visited the Sacred Chalice and made use of its services, with Andrul making use of the Room of Rixx, which contained male prostitutes. Several days later, Lursa and B'Etor visited the establishment and were killed, along with Lwaxana, when Deanna Troi threw a bomb at them. The establishment was then abandoned by all of its workers, as they fled the vengeance of the Alliance. (TNG - Mirror Universe short story: "The Sacred Chalice")

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