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Science minister was the title given to the head of a science ministry.
On Heitius VII circa 7700 BC, the Science Minister converted the king into a cyborg under his control in an attempt to seize power and save his people. (TOS comic: "The Mummies of Heitius VII")
In the mirror universe, Rota Sevrin was appointed Science Minister in the cabinet of Emperor John Gill of the Terran Empire in 2266. (Decipher RPG module: Through a Glass, Darkly)