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Starbase 51 was a Federation space station located near Trill and the Murasaki system.

In the year 2372, the USS Enterprise-E travelled to Starbase 51 for repairs to damage inflicted to the ship by a Changeling infiltrator. (TNG - Slings and Arrows eBook: The Oppressor's Wrong)

In 2376, eight Starfleet starships were operating out of the Starbase, including the USS T'Kumbra, the USS Sagittarius, the USS Polaris and the USS Appalachia. The latter was being refitted in August.

Admiral Leonard James Akaar contacted Starbase 51 in that month from Deep Space 9 to order the starships to engage and destroy the USS Gryphon. (DS9 - Mission Gamma novel: Lesser Evil)

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Federation starbases
Starbases Federation HeadquartersStarfleet Headquarters1234567891011121314151617181920212223242525-Alpha2627282930313233343536373939-Sierra404142434445464747-Vanguard484950515253555658596162636465666768697172737475767779808182838485868788899091929395969799101102103104105106108109112113114117118120121122123126127128129131133134137143144146148152153157162171172173174175176178179180182185188189193197200201202209210211212214215217218219220222223224227231234235236237244247252257260261263264268277295297301302303307309310311312313314315324325326328336343344347357364371375383389393395401410411412413414416419420422434440452473495499505514515516521522523524528535541585592-Epsilon612621623693714718804823834906 (Vanguard)1317Starbase 3141 Romeo407761 CygniAlhenaAndorArdanaBattle Group 1Battle Group 2Battle Group 3Battle Group 4Battle Group 5BethelBravoCopernicusCoridanDenobulaDevalokaDiamandis 1DrozanaEarhartEuropa BaseFleet Setup StationG4G-6HearthHelaspontIcarusIndiaIridaniLambdaLeonovMagellanMI-17MidwayMontgomeryNeil ArmstrongNew XindusOmar StationOutpost Quebec AlphaR-3Regulus StationRigelRisaSeedea BaseSpace Station Sigma OneTazi StationUnity OneVulcanXindus Federation icon image. Starfleet icon image.
Kelvin timeline Starbase 1Starbase 76Starbase 82Starbase 91Frontier 17Starbase YorktownStarbase Zeta
Deep Space Stations 123456789 (I)9 (II)1012161175220253633C-15E-5G-6HubbleK-2K-5K-7K-8K-9K-10K-11K-12K-13K-22KR-1KR-3L-6M-20M-33R-5Repair Beta 6Portal 1
Kelvin timeline K-5K-7K-4K-11