The Trill system is a binary star system in which Trillius Prime, the Trill homeworld, is located. Trill is part of the Kalandra sector in the Alpha Quadrant of the Milky Way Galaxy. (ST reference: Star Charts)

Starbase 51 is the closest Starfleet base to the Trill system. (DS9 - Mission Gamma novel: Lesser Evil)

In 2265, Starfleet discovered a comet heading towards Trill just outside the Trill system. The Starfleet team noted that the comet did not match the cometary halo that surrounded the star system. (DS9 - The Lives of Dax short story: "Sins of the Mother")

In the 31st century, Benjamin Sisko sent a starship carrying the Dax symbiont from the Bajoran wormhole to the Trill system to save the symbiont after its host died in the Gamma Quadrant. (ST short story: "The Law of Averages")

In TNG video game: Birth of the Federation, the orbital configuration of the game map star systems was randomly generated each time a new game started.

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Alpha and Beta Quadrant stars and star systems (T)
TabukTagusTajarhiTakanTakanarraTakoiTalgatTaliTalinTalithaTallusTalnaTalquosTamarosTanarisTaniaTantalusTaosTarazedTarettTarfTariaxTaris SetiTarletusTarnakTarquoleseTarsusTartarusTasusTau BetaTau GammaTaureanTautallusTauteeTaygetaT'DakkaTe AwamutuTechnisTejatTelcosusTeluridianTemarisTemaziTemirTenaraTendarTendarriTenekratusTenberTergaTerratinTerrellianTessmataTevronTewaTezel-OrokoThabitThalakThaliaThark-MorkolTharnosTharsisThasusTheata LeonisThelonii system (Thelonii) • TherbiaThetaTheta 116Theta BowlesTheta CygniTheta GammaTheta HydraeTheta MajorisTheta MarianaTheta MeesTheta RillTheta TauThevosTholusThorian-VThranstorThraxThrazThubanTHX-1138TikopaiTimoniumTir KapovTirosTitanTitaniasTithadiTlaoliTNC-5527TohvunTok'BhulTolochonTomanToolianTorTorgu-VaTornaToronaTortugaTozoxTragerTraklivTrelkisTri-BetalineTri-Rho NauticaTriaminusTriangelesTriangularisT'RillTrillbyTripoliTruxtunTseenTsihTsugh KhaidnnTszeTulanTutakai system (Tutakai) • T'VantTyburnTychoTyoloTyraTyrtaeusTyrus Alpha and Beta Quadrant icon image.
Alpha Quadrant stars and systems (T) TagraTalosTama/TamarTammeronTarahongTarvoTasakTau CetiTau CygnaTau BoötisTegedaarTemeckliaThalosTherbiaTheta DraconisTheta PegasiTL-9139TomedTopinTormanTorrosTrelkaTrillTrivasTyl Alpha Quadrant icon image.
Beta Quadrant stars and systems (T) TalvathTarodTau CentauriTau DeltaTau LacertaeTegmeniTellunTeneebiaTerixTessenTeutilThalassaTheta CentauriTheta CobriniTheta EridaniTheta IndiTheta PavonisTiburonTigelisT'MetToredarTorekTraelusTranome SarTrilith Beta Quadrant icon image.
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