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Memory Beta, non-canon Star Trek Wiki
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The Tzenkethi War was a military conflict waged between the Tzenkethi Coalition and the United Federation of Planets in the mid-24th century.

The USS Okinawa, under Captain James Leyton and first officer Benjamin Sisko, was engaged in action against the Tzenkethi during the war. (DS9 episode: "The Adversary")

Doctor Rebecca Emmanuelli was captured by the Tzenkethi during the war and held as a prisoner for four years. Because of her medical skills, the Tzenkethi listed her as dead after the armistice to avoid returning her to the Federation. After the civilian group Liberation Watch discovered evidence she was in fact alive, Starfleet dispatched the USS Saratoga to investigate. Facing renewed hositilites, the Tzenkethi released the doctor.

Nanietta Bacco's son-in-law was a civilian relief worker during the war. (ST novel: Articles of the Federation)

To date, little has been revealed about the Tzenkethi or their war with the Federation, either canonically or non. Pocket Books editor Marco Palmieri has announced a forthcoming (but as yet unscheduled) novel in The Lost Era series which will focus on this conflict.
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