The USS Brisbane was a Federation Starfleet starship in service in the 24th century.

In 2383, Starfleet ordered the Brisbane to Deep Space 9 to bolster its defenses in case of an attack by the Typhon Pact. Ultimately, it did not arrive in time to defend the station against three Typhon Pact vessels, but it did help securing the Bajoran system in the aftermath of DS9's destruction, including patrolling the Denorios Belt. (ST - Typhon Pact novels: Plagues of Night, Raise the Dawn)

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