The USS Guadalcanal (NCC-4332) was a Federation Larson-class destroyer starship in service to Starfleet in the 23rd century.
The Guadalcanal entered service on reference stardate 1/9108, alongside her Mk I sisterships, USS Iwo Jima and USS Okinawa. She was later refitted to Mk II specifications on reference stardate 1/9907, and to Mk IV specifications on reference stardate 2/0912. Her final refit to Mk VII specifications occured on reference stardate 2/1411. (FASA RPG module: Federation Ship Recognition Manual)