- For other uses, see Jefferson.
The RPG The Dominion War Sourcebook: The Fires of Armageddon, published by Last Unicorn Games after they had lost their Star Trek licence, states that the Jefferson was a heavy participant in the Dominion War as part of Starfleet's Eighth Fleet, spending the first two-thirds of the war defending Andoria and later often fought along the front lines. During the early part of 2374, the Jefferson was commanded by Captain Jenna Piper.
- Possibly named for Thomas Jefferson.
|New Orleans-class starships|
| Federation Starfleet |
|standard configuration||Herbert • Jefferson • Kyushu • Kyushu II • New Orleans • Renegade • Rutledge • Santa Fe • Savannah • Thomas Paine • Tokyo • Yudhisthira|
|variant configurations||Lafayette-subclass: USS Lafayette|
| Terran Empire Starfleet |
|standard configuration||ISS Arnold|