- For other uses, see Neptune.
The USS Neptune was a Defiant-class Federation starship in service in the late 24th century.
In 2376, the Neptune was under the command of Captain Landwaring. The Neptune was the flagship of Task Force Javelin that was sent to locate the source of the Genesis Wave. The Neptune discovered a derelict shuttlepod. One of the Neptune's crewmembers went into the shuttlepod. The Neptune was last heard from in the Boneyard. The Neptune arrived at Myrmidon with no crew. Commander Beverly Crusher of the USS Enterprise-E took a skeleton crew over to the Neptune. An unknown life form infected the crew and the Neptune attacked Myrmidon. The Enterprise transported the crew aboard and the Neptune was destroyed when the Genesis Wave hit. (TNG novels: The Genesis Wave, Book 1, The Genesis Wave, Book 2)