Following this incident, the Odyssey was assigned a patrol of the Demilitarized Zone. However, she was forced to return to DS9 when news reached the station that CommanderBenjamin Sisko and Quark had been taken prisoner by the Jem'Hadar. After offloading all non-essential personnel onto DS9, the Odyssey entered the Gamma Quadrant, accompanied by three runabouts from DS9. The task force was engaged by the Jem'Hadar.
Following the rescue of Commander Sisko and his team the task force began to withdraw, but the Odyssey was rammed by a Jem'Hadar fighter, destroying the starship. (DS9episode: "The Jem'Hadar")