- For other uses, see Sioux.
The USS Sioux (NCC-1621) was a Federation starship, a Malachowski-class vessel in Starfleet service in the 2250s decade. (DSC episode: "Battle at the Binary Stars"; Star Trek Shipyards reference: Starfleet Ships 2151-2293)
On stardate 1207.3 (May 11, 2256), the Sioux was one of two Malachowski-class starships participating in the Battle at the Binary Stars between Starfleet and a Klingon fleet, led by the fanatic T'Kuvma. (DSC episode: "Battle at the Binary Stars")
|Ships named Sioux|
|USS Sioux (NCC-1621, Malachowski-class) • USS Sioux (Defiant-class)|
| Federation Starfleet |
|Asimov • Clarke • Malachowski • Miyamoto • Sioux • Helios-subclass: Zimmerman|
| Terran Imperial Starfleet |
|Starships in the Federation-Klingon War of 2256-2257|
|Federation, Starfleet||USS Discovery • USS Kerala • USS Ride • USS Sebrova • USS Sioux • USS Ticonderoga|
|Federation Starfleet losses||USS Clarke • USS Buran • USS Dana • USS Earhart • USS Edison • USS Europa • USS Gagarin • USS Glenn • USS Hoover • USS Muroc • USS Shran • USS Shenzhou • USS T'Plana-Hath • USS Yeager|
|Klingon Empire, Defense Force||L'Rell's battlecruiser • Sarcophagus|
|Klingon Empire losses||Klingon cleave ship|
- The ship may be named for the Native American Sioux nation.