Vault may refer to:
- Facilities:
- Vault, a laboratory complex on Starbase 47 created to uncover the mystery of the Taurus Reach
- The Vault, a Romulan Star Navy starbase in the Haakona system
- The Vault (Starfleet), a bunker on Earth used as the nerve center of Starfleet Command
- Vault of Tomorrow, a location on Janus VI where the Horta store their eggs
- Religious concepts:
- Vault of Eternal Destitution, the Ferengi equivalent of Hell for those who had been unsuccessful in life
- Vaults of the Dead, a form of the afterlife in one Romulan religion
- Technology:
- Cryogenic vault, a device on Federation starships used to store items at sub-freezing temperatures
- Works:
- "The Vault (STO)", the first mission of the "Cloaked Intentions" featured episode in Star Trek Online
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