Von Holtzbrinck was a Starfleet captain in the mid 23rd century. Circa 2260, von Holtzbrinck became commanding officer of the USS Yorktown, succeeding Matthew Decker. (TOS novel: Prime Directive)
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| USS Yorktown personnel | |||
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| United Earth, Earth Starfleet | USS Yorktown (Daedalus-class) | Albertson • Fleming • Giannini • Krawczak • Mayweather • Mendez • Shosetsu |  
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| Federation, Starfleet | USS Yorktown (Constitution-class) | Akumi • All'o'polla • Amekentra • Arex Na Eth • Beaujolais • Brian • Carlos • Chapel • Conroy • Decker • D'wara • Espinoza • Fenig • Foster • Gaines • Gauvreau • Gibney • Hax • Hodgkins • von Holtzbrinck • Jarboe • Kovic • Lawford • Mahler • M'Benga • Number One • Oshiro • Pike • Pollard • Randall • Randolph • Sanchez • Sudek • Sunak • T'Ark • Thonen • Thursen • Two Rivers • Vashenka |  
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| USS Yorktown (Excelsior-class) | Conlon • Ledbetter • Riker | ||
| USS Yorktown (Zodiac-class) | Kentrav • Hawk • Zimmerman | ||
| USS Yorktown (NCC-1717) (Kelvin timeline) |
Isaac Garrett • 0718 | ||