Wheeler could refer to:
- People
- Wheeler (Operations), an officer aboard the USS Bellerophon
- Wheeler (President), president of Mars
- Wheeler (Yeoman), a yeoman in security aboard the USS Enterprise
- Wheeler Stinson, second officer of Deep Space 9
- Donald Wheeler, a resident of Sherman's Planet
- Janine Wheeler, an ensign aboard the USS Defiant
- John Wheeler, a 20th century physicist
- Scott Wheeler, an officer aboard the USS Voyager
- Tynan Wheeler, a CPO, deputy chief of security of the USS Aldrin
- Anthony Robor-Wheeler, an officer aboard the USS Cooper
- Randall Robor-Wheeler, a master sergeant for the Star Fleet Marines
- Spacecraft
- UNSS Wheeler, a DY-500-class spacecraft
- Real-world topics
- William John Wheeler, a FASA RPG editor
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