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Zeta Gamma 537 was a star system, located somewhere in the space of the Milky Way Galaxy.
The orbit of Zeta Gamma 537 was the location of a planetary system, including a cloaked planet of the Aegis on which Gary Seven was born in 1932. The system was located some fifty thousand light-years from Sol. (TOS - The Eugenics Wars novel: The Rise and Fall of Khan Noonien Singh, Volume 1)